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Journal of Periodontology and Implant Dentistry، جلد ۷، شماره ۱، صفحات ۲۶-۰
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عنوان انگلیسی Efficacy of Photodynamic Therapy as an Adjunct to Full-mouth Root Planing in the Treatment of Periodontitis Assessed by Real-time PCR: A Microbiological and Clinical Study
چکیده انگلیسی مقاله Background and aims. The aim of this investigation was to compare clinical and microbiological effectiveness of ad-junctive photodynamic therapy (PDT) in the treatment of periodontitis. Materials and methods. Twenty-four subjects (14 women and 10 men) diagnosed with moderate to severe chronic periodontitis underwent scaling and root planing (SRP). One tooth in each quadrant (probing depth >4 mm) was selected for combined PDT and SRP (PDT group) with the contralateral tooth (SRP group), as a control site (SRP-treated site). Clinical assessment was carried out at baseline and 1 and 3 month later. Microbial assessment was carried out by real-time PCR. Periodontal probing depth (PPD) was considered as the primary outcome. Results. Baseline PPDs were 4.86±0.77 and 4.04±0.65 in the SRP and PDT groups, respectively (P>0.05), which decreased to 3.65±0.58 in the SRP and 3.86±0.56 in the PDT groups after one month and to 3.20±0.68 in the SRP and 3.34±0.56 in the PDT groups three months later. Although values decreased significantly in both groups after one (P=0.001 in the SRP and P=0.001 in the PDT groups) and three months (P=0.001 in the SRP and P=0.001 in the PDT groups) the inter-group differences were not significant after one (P=0.25) and three months (P=0.51). Clinical measurements showed significant decreases after one and three months at both sites, without inter-group differences, except for bleeding on probing after one (P=0.004) and three months (P=0.0001). Conclusion. Subgingival application of PDT combined with scaling and root planing could not improve clinical and mi-crobiological results.
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نویسندگان مقاله محمد تقی چیت سازی | mohammad taghi chitsazi


عدیله شیرمحمدی | adileh shirmohammadi


مسعود شیرمحمدی | masoud shirmohammadi


اتابک kashefimehr | atabak kashefimehr


ودود قاسمی | vadood ghasemi


نشانی اینترنتی http://dentistry.tbzmed.ac.ir/jpid/index.php/jpid/article/view/210
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Research Article
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