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Journal of Periodontology and Implant Dentistry، جلد ۶، شماره ۲، صفحات ۰-۰
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عنوان انگلیسی Platelet-rich Plasma with Scaling and Root Planing: A Double-blind Split-mouth Randomized Study
چکیده انگلیسی مقاله Background and aims. Along with conventional periodontal therapy, subginigval application of platelet-rich plasma (PRP) may provide more effective improvements in clinical parameters due to the presence of multiple growth factors. The aim of this double-blind, split-mouth, randomized study was to evaluate the adjunctive use of PRP with scaling and root planing (SRP) in the treatment of chronic periodontitis. Materials and methods. A total of 87 non-smokers suffering from moderate to severe chronic periodontitis were se-lected. Parameters were probing pocket depth (PPD), clinical attachment level (CAL), plaque index (PI) and modified bleeding index (mBI). After full-mouth SRP the sites were randomly divided into experimental sites receiving subgingival application of autologous PRP and controls treated with placebo gel. Measurements were recorded at baseline, 3 months and 6 months. Paired t-test was used to compare response to treatment between the two sites. Results. Statistically significant changes in parameters were seen in both groups from baseline to 6 months. Inter-group com-parison revealed significantly more clinical attachment gain for the experimental group (P>0.05). The mean CAL gain was 2.40±0.4 mm for control sites and 2.68±0.5 mm for experimental sites. Conclusion. This study supports the use of PRP during nonsurgical debridement of periodontal pockets measured 6 months after SRP.
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نویسندگان مقاله اشیش agarwal | ashish agarwal


narinder مدیر گوپتا | narinder dev gupta


نشانی اینترنتی http://dentistry.tbzmed.ac.ir/jpid/index.php/jpid/article/view/191
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Research Article
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