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Journal of Dental Research, Dental Clinics, Dental prospects، جلد ۹، شماره ۴، صفحات ۲۶۱-۲۶۶
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Evaluation of the relationship between serum lipid profile and oral lichen planus
چکیده انگلیسی مقاله Background and aims. Oral lichen planus (OLP) is an immunologic disorder. A large number of studies have reported that lipid rafts have a key role in receptor signaling of lymphocytes. Here, we explore the potential of lipid rafts as targets for the development of a new class of agents to down-modulate immune responses and treat autoimmune diseases. Materials and methods. The present cross-sectional study evaluated 88 patients referring to the Department of Oral Medicine in 3 groups (Group 1: erosive OLP; Group 2: non-erosive OLP; Group 3: healthy). A total of 3 mL of blood sample was taken from each subject and the serum levels of cholesterol, triglycerides, HDL and LDL were determined. The mean outcomes of each group were compared with each other and analyzed two by two. Results. The results of statistical analyses showed no significant differences in mean HDL and LDL serum levels between the three groups. The results of post hoc LSD test showed that mean serum levels of subjects with erosive and non-erosive lichen planus were higher than those in healthy subjects. In relation to triglyceride serum levels, the mean serum levels of triglycerides were higher in erosive and non-erosive OLP patients compared to healthy subjects. Conclusion. Triglyceride and cholesterol can be considered to have a critical role in the incidence of lichen planus and in its manifestations as predisposing factors.
کلیدواژه‌های انگلیسی مقاله Lichen planus,serum,lipid profile
نویسندگان مقاله معصومه مهدی پور | masoumeh mehdipour
associate professor, department of oral and maxillofacial medicine, faculty of dentistry, shahid beheshti university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

علی تقوی زنوز | ali taghavi zenouz
associate professor, department of oral and maxillofacial medicine, faculty of dentistry, tabriz university of medical sciences, tabriz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تبریز (Tabriz university of medical sciences)

فرناز داودی | farnaz davoodi
post graduate student of operative dentistry


نرگس قلی زاده | narges gholizadeh
assistant professor, department of oral and maxillofacial medicine, faculty of dentistry, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسین دامغانی | hossein damghani


ساناز حلی | sanaz helli
assistant professor, department of oral and maxillofacial medicine, faculty of dentistry, ardabil university of medical sciences, ardabil, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اردبیل (Ardabil university of medical sciences)

مریم صفرنواده | maryam safarnavadeh
assistant professor, educational deputy of ministry of health and medical education, tehran, iran

سازمان اصلی تایید شده: وزارت بهداشت درمان و آموزش پزشکی (Ministry of health and medical education)

نشانی اینترنتی http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/1748
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/183/article-183-319659.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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