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Journal of Dental Research, Dental Clinics, Dental prospects، جلد ۹، شماره ۲، صفحات ۱۰۹-۱۱۴
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عنوان انگلیسی Relationship of salivary lactoferrin and lysozyme concentrations with Early Childhood Caries
چکیده انگلیسی مقاله Background and aims. Lysozyme and lactoferrin are salivary proteins which play an important role in innate defense mechanisms against bacteria. This study investigated the association of salivary lysozyme and lactoferrin concentrations with early childhood caries (ECC). Materials and methods. This study was carried out on 42 healthy children (age range, 36 to 71 months), of whom 21 were caries free (CF) and 21 had ECC. Disposable needle-less syringes were used to collect unstimulated saliva from buccal and labial vestibules. Fifteen children who had ECC were treated completely and their saliva was collected in the same way for the second time, three months after treatment. Lysozyme and lactoferrin concentrations were measured and recorded by the ELISA method. The intergroup comparisons were carried out using chi-square, Student’s t-test and Wilcoxon signed ranked test. A P-value less than 0.05 was considered as statistically significant. Results. The mean concentration of lysozyme was significantly higher in CF group compared with that of ECC group (P = 0.04). Although the mean concentration of lactoferrin in ECC group was higher in comparison with ECC group, the difference was not statistically significant (P = 0.06). After dental treatment, the mean concentrations of lysozyme and lactoferrin did not change in comparison with their concentrations before treatment. Conclusion. ECC may have a relationship with lower concentrations of unstimulated salivary lactoferrin and lysozyme and reduced amounts of these two salivary proteins may be a risk factor for dental caries in children.
کلیدواژه‌های انگلیسی مقاله Dental caries, lactoferrin, lysozyme, saliva
نویسندگان مقاله معصومه مسلمی | masoumeh moslemi
shahid beheshti medical sciences university


ماندانا ستاری | mandana sattari


فهیمه کوشکی | fahimeh kooshki


فایزه فتوحی | faezeh fotuhi


ندا مدرسی | neda modarresi


زهرا خلیلی صدرآباد | zahra khalili sadrabad


محمد سعید شادکار | mohammad saeid shadkar
phd student in economics, faculty of economics, tehran university, tehran, iran

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

نشانی اینترنتی http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/1605
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/183/article-183-319684.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Article
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