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Journal of Dental Research, Dental Clinics, Dental prospects، جلد ۹، شماره ۱، صفحات ۴۹-۵۲

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عنوان انگلیسی Effect of fluoride, chlorhexidine and fluoride-chlorhexidine mouthwashes on salivary Streptococcus mutans count and the prevalence of oral side effects
چکیده انگلیسی مقاله Background and aims. Streptococcus mutans is the main pathogenic agent involved in dental caries, and may be eliminated using mouthwashes. The objective of this study was to compare the effects of fluoride, chlorhexidine, and fluoride-chlorhexidine mouthwashes on salivary S. mutans count after two weeks of use and determine the prevalence of their side effects on the oral mucosa. Materials and methods. In this clinical trial, 120 12-14 year-old students were selected and divided into three groups. Each group was given one of fluoride, chlorhexidine, or fluoride-chlorhexidine mouthwashes. They were asked to use it twice a day for two weeks. Salivary samples were collected at baseline and after two weeks. Data were analyzed by Wilcoxon and Kruskal-Wallis tests. Results. In all the study groups, there were statistically significant reductions in salivary S. mutans counts two weeks after using the mouthwashes (P < 0.05). In addition, fluoride-chlorhexidine mouthwash had a significant effect on the reduction of S. mutans count in comparison with fluoride alone. The prevalence of oral side effects in fluoride-chlorhexidine mouthwash was more than 90%. Conclusion. Adding fluoride to chlorhexidine mouthwash can significantly decrease salivary S. mutans count after two weeks. Fluoride-chlorhexidine has the highest rate of oral side effects between the evaluated mouthwash compounds.
کلیدواژه‌های انگلیسی مقاله Chlorhexidine,fluoride,Streptococcus mutans

نویسندگان مقاله فاطمه سادات سجادی | fatemeh sadat sajadi
assistant professor ,department of pediatric dentistry , faculty of dentistry, member of kerman oral amp;amp;dental diseases researches centre, kerman university of medical sciences, kerman-iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

محمدمرادی | mohammad moradi
ph d, assistant professor of medical microbiology and member of research center for tropical and infectious diseases, kerman university of medical sciences, medical school, kerman, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

عباس پرداختی | abbas pardakhty
professor of neuropharmacology institute, pharmaceutics research center, kerman university of medical sciences, kerman-iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

راضیه یزدی زاده | razieh yazdizadeh
dentist


فایزه مدنی | faezeh madani
rezident of pediatric dentistry,kerman university of medical sciences, dental school, kerman-iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)


نشانی اینترنتی http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/1436
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/183/article-183-319697.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Short Communication
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