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Journal of Dental Research, Dental Clinics, Dental prospects، جلد ۴، شماره ۱، صفحات ۲۵-۲۸
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عنوان انگلیسی Comparison of the effect of mouthwashes with and without zinc and fluocinolone on the healing process of erosive oral lichen planus
چکیده انگلیسی مقاله Background and aims. Lichen planus is a chronic inflammatory disorder with unspecified etiology, appearing as a result of stress, genetic predisposition and immunologic factors. Erosive type of the disease is more important because of its clinical symptoms of pain, irritation and malignancy risk. Despite various medications used, a definite cure for lichen planus is unknown. Regarding the effect of zinc on healing of ulcers, the aim of this study was to compare the effect of a mouthwash with and without zinc and fluocinolone on healing of erosive oral lichen planus. Materials and methods. Twenty randomly-selected patients with erosive oral lichen planus were divided into two groups of 10. One group received zinc mouthwash with fluocinolone ointment and the other group received placebo with ointment. The largest dimension of the ulcers was measured by digital calipers and the intensity of pain was determined by visual analogue scale. Data was analyzed with Mann-Whitney U test. Results. Pain, irritation and lesion surface area decreased in both groups. Decrease in pain severity was identical in both groups (P = 0.11). However, decrease in surface area with zinc mouthwash plus fluocinolone was more than that with only fluocinolone (P = 0.037). Conclusion. 0.2% zinc mouthwash plus fluocinolone and only fluocinolone were both effective in decreasing pain, irritation, and surface area of OLP. However, decrease in surface area with zinc mouthwash plus fluocinolone was more than that with fluocinolone alone.
کلیدواژه‌های انگلیسی مقاله Fluocinolone ointment,oral lichen planus,zinc mouthwash
نویسندگان مقاله معصومه مهدی پور | masoumeh mehdipour


علی تقوی زنوز | ali taghavi zenouz


آیلا بهرامیان | aila bahramian


جواد یزدانی | javad yazdani


فیروز پورعلی بابا | firoz pouralibaba


کتایون صدر | katayoun sadr


نشانی اینترنتی http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/130
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/183/article-183-319882.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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