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Journal of Dental Research, Dental Clinics, Dental prospects، جلد ۱، شماره ۳، صفحات ۱۰۸-۱۱۳
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عنوان انگلیسی Epidemiology of Pemphigus in Tehran, Iran: A 20-Year Retrospective Study
چکیده انگلیسی مقاله Background and aims. Pemphigus is a chronic autoimmune and vesiculobollous disease that can affect skin and different mucous membrane surfaces. Primary manifestations occur in oral cavity in almost 60% of cases. The purpose of the present study was to evaluate the epidemiology of pemphigus in Tehran, Iran in a 20-year period. Materials and methods. A retrospective study was conducted on the records of 1560 patients diagnosed with different types of pemphigus in Razi Hospital of Dermatology in Tehran from March 1985 to March 2005. A questionnaire was prepared to collect information regarding age, sex, bedridden duration, pemphigus subtype, sites of involvement, recurrence and mortality rate. Data was analyzed using chi-square test with significant level of P Results. There was a female predominance with a male to female ratio of 1:1.53. In nearly half of the patients, only the oral mucous membranes were affected. One hundred and fifty had only skin lesions and 261 cases had both skin and oral mucosal lesions. Involvement of esophageal and vaginal mucous membranes without skin lesions was observed in 150 patients and 298 cases had esophageal and vaginal mucosal involvement as well as skin lesions. Pemphigus vulgaris was the most common type, with the mean age of 44.6 years. Oral mucous membrane was the most frequent location where pemphigus vulgaris was observed. 1265 patients recovered which 52.2% of them had only oral lesions. Average of bedridden duration was 2.9 months. The highest recurrence rate was seen in patients with skin lesions exclusively. There was a significant difference between recurrences of lesions and location of involvement (P Conclusion. The mean age of the disease onset in the present study was found to be a decade earlier than the other parts of the world. Recurrence and mortality rates were lower in patients with only oral lesions and their prognosis was better.
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نویسندگان مقاله حمید رضا عبدالصمدی | hamid reza abdolsamadi


شرمین عبداله زاده | shermin abdollahzadeh


پژمان بکیانیان وزیری | pejman bakianian vaziri


اکرم بهشتی | akram beheshti


الناز شفیق | elnaz shafigh


محمد واحدی | mohammad vahedi


نشانی اینترنتی http://dentistry.tbzmed.ac.ir/joddd/index.php/joddd/article/view/19
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/183/article-183-319946.pdf
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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